Quality Standard: USP31
Appearance: White Crystalline Powder
Usage: Adrenal Cortical Hormone and Adrenocorticotropic
Clobetasol propionate is a corticosteroid used to treat various
skin disorders including eczema and
psoriasis. is also highly effective for contact dermatitis caused
by exposure to poison ivy/oak.
Clobetasol belongs to US Class I of the corticosteroids, making it
one of the most potent available. It comes in shampoo, mousse,
ointment and emollient cream presentations. It has very high
potency and typically should not be used with occlusive dressings,
or for extended continuous use (beyond two weeks). It is also used
to treat several auto-immune diseases including alopecia areata,
vitiligo and lichen planus.
1. Anti-inflammatory effects: The product can reduce and prevent
tissue response to inflammation, thereby reducing inflammation
performance. Hormone suppression of inflammatory cells, including
leukocytes and macrophages accumulation in sites of inflammation
and inhibition of phagocytosis, lysosomal enzyme release and
synthesis and release of inflammatory chemical mediators. Can
reduce and prevent tissue response to inflammation, thereby
reducing inflammation performance.
2. Immunosuppressive effect: preventing or inhibiting cell-mediated
immune response, delayed hypersensitivity reactions, reducing T
lymphocytes, monocytes, eosinophils, reducing immunoglobulin
binding to cell surface receptors and inhibition of the synthesis
and release of interleukin, thus reducing the T lymphocyte
transformation of lymphoblastoid cells, and reduce the extension of
the primary immune response. Can reduce immune complexes through
the basement membrane, and can reduce the concentration of
ingredients complement and immunoglobulins.
Clobetasol Propionate COA